Imagine if an app could learn your taste in beer the way Netflix learns your taste in movies. It's coming. Drink it all in.
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মঙ্গলবার, ৩০ এপ্রিল, ২০১৩
Ergotech VersaStand
There's an endless array of stands and cases made for protecting and propping up the Apple iPad. The ErgoTech VersaStand ($99 list) happens to be a combination of both, with a snap-on case and a sturdy aluminum stand. The slick collapsible stand looks great and offers a nearly infinite variety of angles, and it's a cinch to get the iPad on and off the stand. You're paying a premium for design here, as there are plenty of more affordable, generic stands available, but if you use your iPad primarily as a desktop display, the VersaStand is a more-than-capable option.
With a black soft-touch plastic body, the snap-on case is pretty standard, but around back there's an aluminum ring that protrudes about a quarter inch. There are cutouts for the iPad's ports and buttons, with a cutout along the left edge so you can use Apple's Smart Cover with the case. The VersaStand is compatible with the iPad 2, the third-gen iPad, and the most recent fourth-gen iPad. I tested the VersaStand with both the iPad 2 and fourth-gen iPad and each fit perfectly.
The stand is made almost entirely from hinged, brushed aluminum segments, with a small disk at the end of the articulating arm that attaches to the ring on the case. There are two buttons on either side of the disc, which you press down to attach and remove the iPad. The case and stand are similar to the Wallee case system, which has an optional aluminum Pivot stand.?
You can turn the tablet Pad a full 360 degrees once snapped in, but the stand itself does not swivel left or right. The articulating arm allows for any viewing angle imaginable, and the stand feels sturdy when placed on a flat surface. While it's not difficult to adjust the stand, you will have to hold the base down with your free hand. The stand unit also neatly collapses down for transport.
You have a lot of options when it comes to iPad stands, and while the VersaStand is an attractive combination of form and function, it's not cheap. It's also clearly suited for desk use, whereas something like the Speck HandyShell?would make a better choice if you want to move the stand around frequently. The VersaStand is also on the tall side for stands, which makes it a good option for those who want to use their iPads next to, say, a desktop monitor.?And if function trumps form, there are plenty of inexpensive generic plastic stands that will do the same things as the VersaStand.
Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/ZAP6cC942t8/0,2817,2418153,00.asp
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Ed Helms' 'Tiny Commando' series coming to Yahoo
NEW YORK (AP) ? Yahoo's latest slate of original programming is led by Ed Helms as a 4-inch-tall crime fighter.
"Tiny Commando," created by the "The Office" star, was unveiled Monday night in a presentation by Yahoo to advertisers in New York. It stars Helms, along with Zachary Levi, of "Chuck," and Gillian Jacobs, of "Community."
Following in Netflix's footsteps, Yahoo will simultaneously release all episodes of "Tiny Commando" and other comedy series this fall.
Yahoo, based in Sunnyvale, Calif., also will debut a series titled "Losing Your Virginity With John Stamos," in which the former "Full House" actor interviews celebrities about their first sexual experiences. Documentary filmmaker Morgan Spurlock executive produces.
Along with YouTube, Netflix and Hulu, Yahoo has sought in recent years to expand into original programming ? mainly short-form Web series ? that draws users to its platform. Erin McPherson, Yahoo vice president and head of video, said the company has more than doubled its original video programming in the last year.
Yahoo's presentation Monday was part of this week's Digital Content NewFronts, at which digital media companies lay out their programming plans much like TV broadcasters do every spring. Last year, Yahoo touted its most high-profile series: Tom Hanks' sci-fi, animated "Electric City." While "Electric City" was widely judged a dud, Yahoo has found a modest hit in "Burning Love," a parody of "The Bachelor" now beginning its third season.
Also part of this year's slate is Cheryl Hines, a star of "Curb Your Enthusiasm." Hines and Rachael Harris will star in "We Need Help," a comedy in which the two actresses exploit a shared personal assistant.
Yahoo announced that beginning this summer it's partnering with the WWE to make the Web portal an online hub for professional wrestling videos. Yahoo will produce a 30-minute pre-show to the WWE's "Monday Night Raw" and distribute two weekly wresting series.
Last week, Yahoo announced a deal to stream "Saturday Night Live" archival clips.
___
Follow AP Entertainment Writer Jake Coyle on Twitter at: http://twitter.com/jake_coyle
Source: http://news.yahoo.com/ed-helms-tiny-commando-series-coming-yahoo-230336152.html
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Senator Paul stirs business ire over blocking of tax treaties
By Patrick Temple-West
WASHINGTON (Reuters) - Senator Rand Paul is coming under pressure from some multi-national businesses to drop his opposition to tax treaties between the United States and other nations.
Citing privacy concerns about Americans' tax data, Paul, a Republican and libertarian, has single-handedly blocked Senate action on treaties with Hungary, Switzerland and Luxembourg that have been signed by authorities on both sides, but have been awaiting Senate review since 2011.
At least six other tax treaties or treaty updates -- with Chile, Spain, Poland, Japan, Norway and Britain -- may soon be added to the Senate's queue for confirmation votes.
Major U.S. businesses such as IBM Corp and Fluor Corp are lobbying for Senate action on tax treaties, according to Senate lobbying disclosure documents.
"How many treaties will be held hostage?" asked Cathy Schultz, a lobbyist for the National Foreign Trade Council, a Washington, D.C.-based group that represents companies such as Caterpillar Inc and Pfizer Inc.
Paul has said he is concerned that recent treaties would give foreign governments too much access to U.S. citizens' tax information, a stance that has some support among like-minded conservative libertarians.
"Rand Paul is not a typical senator who may bend over to business lobbyists," said Chris Edwards, director of tax policy at The Cato Institute, a libertarian think tank.
"I am very concerned about this increasingly aggressive international exchange of information," Edwards said.
NO APPROVALS SINCE 2010
No new tax treaties or treaty updates have been approved since 2010, when Paul was elected as the junior senator from Kentucky on a wave of support for Tea Party-aligned Republicans.
Paul recently declined to answer questions from a reporter in a Capitol hallway about the "hold" he has placed on the treaties. Under Senate rules, one senator can prevent a motion from reaching a vote on the Senate floor.
Paul's staff did not reply to repeated requests for comment.
"There's never really been an objection of this sort and a hold that's gone on this long," said Nancy McLernon, president of the Organization for International Investment, which lobbies in Washington on behalf of foreign companies.
In an effort to sway the senator, McLernon said her group would be lobbying both parties to draw attention to the tax treaties. "Let's stop with the self-inflicted wounds," she said.
The United States has tax treaties with more than 60 countries, ranging from China to Kyrgyzstan.
The agreements previously have routinely won Senate approval with little controversy and accomplished their main purpose of preventing double-taxation of income and profits.
In recent years, tax treaties have begun to play an increasing role in efforts by the United States and major European Union countries to crack down on tax avoidance.
The U.S. Treasury in 2012 began signing new tax pacts with countries as part of implementation of the U.S. Foreign Account Tax Compliance Act, a 2010 anti-tax-evasion law.
The law, known as FATCA, which takes effect in January 2014, will require foreign financial institutions to disclose to the United States information about Americans' accounts worth more than $50,000.
SWISS A DRIVING FORCE
Switzerland, a long-time bastion of banking secrecy, is under international pressure to change its ways, and FATCA has been a driving force in that. The United States and Switzerland in February signed a FATCA implementation agreement that would make more information available to U.S. authorities about the financial interests of Americans in Switzerland.
But the taxpayer information exchange cannot go into force without Senate approval of the U.S.-Swiss tax treaty.
The Senate's delayed action on tax treaties could convince other countries to stop negotiating with the United States on tax matters, said John Harrington, a former Treasury tax official who is now a partner at law firm SNR Denton.
Paul, seen as a possible 2016 presidential contender, has taken a position that sets up a clash of traditional Republican interest groups: big business and libertarian ideologues.
In this sense, Paul is in the forefront of the party's search for a new identity since Republicans lost the presidential race last year, as well as numerous seats in the House of Representatives.
Looking toward a possible 2016 White House bid, Paul told reporters earlier this month that he will visit early-voting states this year and make a final decision next year.
New Republicans such as Paul are shifting the party away from its business-first agenda, said Dan Holler, communications director for Heritage Action, a conservative group.
"The party is not being reflexively pro-business," he said.
(Reporting by Patrick Temple-West; Editing by Kevin Drawbaugh and Leslie Adler)
Source: http://news.yahoo.com/senator-paul-stirs-business-ire-over-blocking-tax-165604737.html
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সোমবার, ২৯ এপ্রিল, ২০১৩
UFC 159 was clearly cursed by demons (Video)
"It was a very weird night."
UFC president Dana White started the post-UFC 159 press conference with these words. The event featured a nasty broken thumb on Yancy Medeiros, and equally nasty broken toe on Jon Jones, two fight stoppages because of eyepokes, and one fight that was canceled hours before it was supposed to happen.
But the craziest part of all? The demonic voice that was heard between rounds of Michael Bisping's win over Alan Belcher.
Did the gates of hell open before the fight, and did Satan send his minions to New Jersey? Were Bisping's cornermen, who were bathed in creepy red light, actually demons? Middle Easy thinks it was a spell from "Passages of the Dead."
It's possible the UFC ticked off the wrong person and got the evil eye thrown its way. The bigger question: Are we all cursed for watching the bouts?
Source: http://sports.yahoo.com/blogs/mma-cagewriter/ufc-159-clearly-cursed-demons-video-172924960.html
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Boston suspects' father postpones trip to U.S.
MAKHACHKALA, Russia (AP) ? The father of the two Boston bombing suspects said Sunday that he has postponed a trip from Russia to the United States because of poor health.
"I am really sick," Anzor Tsarnaev, 46, told The Associated Press. He said his blood pressure had spiked to dangerous levels.
Tsarnaev said at a news conference Thursday that he planned to leave that day or the next for the U.S. with the hope of seeing his younger son, who is under arrest, and burying his elder son, who was killed. His family, however, indicated later Thursday that the trip could be pushed back because he was not feeling well.
Tsarnaev confirmed on Sunday that he is staying in Chechnya, a province in southern Russia, but did not specify whether he was hospitalized. He is an ethnic Chechen and has relatives in Chechnya, although he and his family spent little time in Chechnya or anywhere else in Russia before moving to the U.S. a decade ago.
He and the suspects' mother, Zubeidat Tsarnaeva, returned to Russia last year and settled in Makhachkala, the capital of neighboring Dagestan, where Tsarnaeva's relatives live.
During the past week, they were both questioned extensively by U.S. investigators who had traveled to Makhachkala from Moscow. They also were besieged by journalists who staked out their home.
Tsarnaev's family said last week that he intended to get to the U.S. by flying from Grozny, the Chechen capital, to Moscow. He and Tsarnaeva left Dagestan on Friday, but their whereabouts were unclear.
Source: http://news.yahoo.com/boston-suspects-father-postpones-trip-us-124041600.html
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Daily Chronicle | Are lesbians more accepted than gay men?
CHICAGO ? It may be a man?s world, as the saying goes, but lesbians seem to have an easier time living in it than gay men do.
High-profile lesbian athletes have come out while still playing their sports, but not a single gay male athlete in major U.S. professional sports has done the same. While television?s most prominent same-sex parents are the two fictional dads on ?Modern Family,? surveys show that society is actually more comfortable with the idea of lesbians parenting children.
And then there is the ongoing debate over the Boy Scouts of America proposal to ease their ban on gay leaders and scouts.
Reaction to the proposal, which the BSA?s National Council will take up next month, has been swift and often harsh. Yet amid the discussions, the Girl Scouts of USA reiterated their policy prohibiting discrimination based on sexual orientation, among other things. That announcement has gone largely unnoticed.
Certainly, the difference in the public?s reaction to the scouting organizations can be attributed, in part, to their varied histories, including the Boy Scouts? longstanding religious ties and a base that has become less urban over the years, compared with the Girl Scouts?.
But there?s also an undercurrent here, one that?s often present in debates related to homosexuality, whether over the military?s now-defunct ?Don?t Ask, Don?t Tell? policy or even same-sex marriage. Even as society has become more accepting of homosexuality overall, longstanding research has shown more societal tolerance for lesbians than gay men, and that gay men are significantly more likely to be targets of violence.
That research also has found that it?s often straight men who have the most difficult time with homosexuality ? and particularly gay men ? says researcher Gregory Herek.
?Men are raised to think they have to prove their masculinity, and one big part about being masculine is being heterosexual. So we see that harassment, jokes, negative statements and violence are often ways that even younger men try to prove their heterosexuality,? says Herek, a psychologist at the University of California, Davis, who has, for years, studied this phenomenon and how it plays out in the gay community.
That is not, of course, to downplay the harassment lesbians face. It can be just as ugly.
But it?s not as frequent, Herek and others have found, especially in adulthood. It?s also not uncommon for lesbians to encounter straight men who have a fascination with them.
?The men hit on me. The women hit on me. But I never feel like I?m in any immediate danger,? says Sarah Toce, the 29-year-old editor of The Seattle Lesbian and managing editor of The Contributor, both online news magazines. ?If I were a gay man, I might ? and if it?s like this in Seattle, can you imagine what it is like in less-accepting parts of middle America??
One of Herek?s studies found that, overall, 38 percent of gay men said that, in adulthood, they?d been victims of vandalism, theft or violence ? hit, beaten or sexually assaulted ? because they were perceived as gay. About 13 percent of lesbians said the same.
A separate study of young people in England also found that, in their teens, gay boys and lesbians were almost twice as likely to be bullied as their straight peers. By young adulthood, it was about the same for lesbians and straight girls. But in this study, published recently in the journal Pediatrics, gay young men were almost four times more likely than their straight peers to be bullied.
At least one historian says it wasn?t always that way for either men or women, whose ?expressions of love? with friends of the same gender were seen as a norm ? even idealized ? in the 19th century.
?These relationships offered ample opportunity for those who would have wanted to act on it physically, even if most did not,? says Thomas Foster, associate professor and head of the history department at DePaul University in Chicago.
Today?s ?code of male gendered behavior,? he says, often rejects these kinds of expressions between men.
We joke about the ?bro-mance? ? a term used to describe close friendships between straight men. But in some sense, the humor stems from the insinuation that those relationships could be romantic, though everyone assumes they aren?t.
Call those friends ?gay,? a word that?s still commonly used as an insult, and that?s quite another thing. Consider the furor over Rutgers University men?s basketball coach Mike Rice, who was recently fired for mistreating his players and mocking them with gay slurs.
If two women dance together at a club or walk arm-in-arm down the street, people are usually less likely to question it ? though some wonder if that has more to do with a lack of awareness than acceptance.
?Lesbians are so invisible in our society. And so I think the hatred is more invisible,? says Laura Grimes, a licensed clinical social worker in Chicago whose counseling practice caters to gay, lesbian, bisexual and transgender clients.
Grimes says she also frequently hears from lesbians who are harassed for ?looking like dykes,? meaning that people are less accepting if they look more masculine.
Still, Ian O?Brien, a gay man in Washington, D.C., sees more room for women ?to transcend what femininity looks like, or at least negotiate that space a little bit more.?
O?Brien, who?s 23, recently wrote an opinion piece tied to the Boy Scout debate and his own experience in the Scouts when he was growing up in the San Diego area.
?To put it simply: Being a boy is supposed to look one way, and you get punished when it doesn?t,? O?Brien wrote in the piece, which appeared in The Advocate, a national magazine for the gay, lesbian, bisexual and transgender communities.
Joey Carrillo, a gay student at Elmhurst College in suburban Chicago, remembers trying to be as masculine as possible in high school. He hid the fact that he was gay, particularly around other athletes. As a wrestler, he says he never wanted to hear someone say, ?Oh, THAT?S why he wrestles.?
In fact, though more gay and lesbian athletes are coming out in college, gay male professional athletes in major sports have waited to do so until they have left their sport, one of the more recent being Robbie Rogers, an American soccer player who played professionally in England. There have been reports that gay male athletes who are currently playing may be on the verge of going public.
But women have already done so with little backlash.
U.S. soccer star Megan Rapinoe, for instance, came out right before she played in last year?s Olympics. WNBA star Seimone Augustus and the league?s No. 1 draft pick, Brittney Griner, are some of the more recent female athletes to follow suit.
In Hollywood in recent years, both openly gay men and lesbians have had successful careers. And when it comes to television and movies, it appears there are more high-profile gay male characters.
Still, while many see the two dads on the ?Modern Family? sitcom as groundbreaking, others have a sense that the societal discomfort with gay men as parents is at the root of many of the jokes.
?A good portion of that is for comedic effect,? says Don Todd, a 32-year-old father in a two-dad family in Orange, Calif. He doesn?t think most people would think it was as funny if the characters were two moms.
Herek, the researcher at UC-Davis, has, in fact, found in surveys that heterosexuals think lesbians would be better parents than gay men.
Nancy Dreyer, a mother in a two-mom family, has noticed this in her own life.
?With gay male friends of ours who have kids, people will say, ?My gosh, who takes care of this baby?? ? as if they?re not capable,? says Dreyer, whose 57 and lives in suburban Boston.
The assumption, she says, is that men aren?t nurturing. And if they?re too nurturing, she says, people get suspicious, noting that no one has ever questioned her and her partner about their ability to raise their son, who?s now in college.
She?s noticed the different ways society treats gay men and lesbians, partly because she has a brother, Benjamin Dreyer, who?s gay. The Dreyer siblings say it?s difficult to compare their experiences because Benjamin came out in college, and Nancy in her early 30s.
So he was the first to tell their parents. ?They yelled at me. They took you to dinner,? Benjamin Dreyer, who?s 54 and works in publishing in New York City, now jokes with his sister.
Truth was, as a young gay man coming of age as the AIDS epidemic took hold, his parents simply worried, and with good reason, his sister says.
There?s little doubt, they both say, that AIDS influenced the perception of gay men.
Benjamin Dreyer says he dealt with societal bias by avoiding it, and surrounding himself with people he knew would be supportive, including his parents, eventually.
But he?s also realizing how quickly the need to do that is disappearing. He was surprised and pleased, for instance, when he attended his nephew?s high school graduation last year. There, he saw a gay male graduate with his boyfriend, open and accepted by all his peers.
?It?s mind-boggling,? Benjamin Dreyer says. ?It?s wonderful.?
Carrillo, too, decided to live openly when he arrived at Elmhurst College. He joined a fraternity and even painted a rainbow ? a common symbol of the gay community ? on his fraternity paddle. To his surprise, there was some backlash from a couple of his straight fraternity brothers who feared people would think their fraternity was the ?gay fraternity.?
?There?s a long way to go,? says Carrillo, who graduates next month. But he still feels hopeful.
?Honestly, I see it ? everywhere there?s progress.?
___
Martha Irvine is an AP national writer. She can be reached at mirvine(at)ap.org or at http://twitter.com/irvineap
There are 27 hours, 2 minutes remaining to comment on this story.
Source: http://www.daily-chronicle.com/2013/04/27/are-lesbians-more-accepted-than-gay-men/ao2g0gn/
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Supreme Court won't lift block on Alabama immigration law
By Lawrence Hurley
WASHINGTON (Reuters) - The Supreme Court on Monday rebuffed the state of Alabama, and gave a win to the Obama administration, by declining to review a lower court ruling that had blocked a controversial part of the state's tough immigration law.
Alabama had asked the high court to review an appeals court decision to stop enforcement of the 'harboring' provision that made it illegal to harbor or transport anyone in the state who had entered the country illegally.
The appeals court had acted in 2012 at the Obama administration's request. The White House had said that Alabama's law was trumped by federal immigration law.
The Alabama law, enacted in 2011, is considered one of the toughest state immigration statutes in the nation. The law also made it illegal to encourage people to either enter or stay in the country in violation of federal immigration laws.
The Atlanta-based 11th U.S. Circuit Court of Appeals, in two separate decisions, upheld injunctions against the harboring provision and other parts of the law in August 2012.
A brief order issued by the court on Monday said Justice Antonin Scalia disagreed with the decision not to hear the case.
The Obama administration has challenged other provisions of the Alabama law, but they were not at issue in the case before the high court.
In 2012, the justices partially upheld a similar wide-ranging law enacted in Arizona.
Arizona and eight other states have similar laws. Laws in Georgia and South Carolina are also being challenged in court.
The case is Alabama v. United States, U.S. Supreme Court, No. 12-884.
(Reporting by Lawrence Hurley; Editing by Kevin Drawbaugh and Jackie Frank)
Source: http://news.yahoo.com/justices-decline-review-alabama-immigration-law-134547712.html
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Reports: Cops shot outside Italian premier office
ROME (AP) ? Reports say two paramilitary police officers were shot and wounded outside the Italian premier's office as the new leader was sworn in about a kilometer (half-mile) away.
An AP television producer reported seeing one officer lying on the pavement, with blood pouring out of his neck. The Italian news agency ANSA said the assailant, described in reports as a man dressed in a suit and tie, had been detained by police.
The shooting came as Enrico Letta and his Cabinet took their oaths Sunday in the Quirinal presidential office, after he nailed down a coalition agreement between his center-left forces and the conservative bloc of ex-Premier Silvio Berlusconi.
It was unclear if there was any connection between the events, but political tensions have been running high in Italy.
Source: http://news.yahoo.com/reports-cops-shot-outside-italian-premier-office-100457952.html
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Cyberattack suspect had 'bunker' in north Spain
MADRID (AP) ? A Dutch citizen arrested in northeast Spain on suspicion of launching what is described as the biggest cyberattack in Internet history operated from a bunker and had a van capable of hacking into networks anywhere in the country, officials said Sunday.
The suspect traveled in Spain using his van "as a mobile computing office, equipped with various antennas to scan frequencies," an Interior Ministry statement said.
Agents arrested him Thursday in the city of Granollers, 35 kilometers (22 miles) north of Barcelona, complying with a European arrest warrant issued by Dutch authorities.
He is accused of attacking the Swiss-British anti-spam watchdog group Spamhaus whose main task is to halt ads for counterfeit Viagra and bogus weight-loss pills reaching the world's inboxes.
The statement said officers uncovered the computer hacker's bunker, "from where he even did interviews with different international media."
The 35-year-old, whose birthplace was given as the western Dutch city of Alkmaar, was identified only by his initials: S.K.
The statement said the suspect called himself a diplomat belonging to the "Telecommunications and Foreign Affairs Ministry of the Republic of Cyberbunker."
Spanish police were alerted in March by Dutch authorities of large denial-of-service attacks being launched from Spain that were affecting Internet servers in the Netherlands, United Kingdom and the U.S. These attacks culminated with a major onslaught on Spamhaus.
The Netherlands National Prosecution Office described them as "unprecedentedly serious attacks on the nonprofit organization Spamhaus."
The largest assault clocked in at 300 billion bits per second, according to San Francisco-based CloudFlare Inc., which Spamhaus enlisted to help it weather the onslaught.
Denial-of-service attacks overwhelm a server with traffic, jamming it with incoming messages. Security experts measure the attacks in bits of data per second. Recent cyberattacks ? such as the ones that caused persistent outages at U.S. banking sites late last year ? have tended to peak at 100 billion bits per second, one third the size of that experienced by Spamhaus.
Netherlands, German, British and U.S. police forces took part in the investigation leading to the arrest, Spain said.
The suspect is expected to be extradited from Spain to face justice in the Netherlands.
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How does pregnancy reduce breast cancer risk?
Apr. 28, 2013 ? Being pregnant while young is known to protect a women against breast cancer. But why? Research in BioMed Central's open access journal Breast Cancer Research finds that Wnt/Notch signalling ratio is decreased in the breast tissue of mice which have given birth, compared to virgin mice of the same age.
Early pregnancy is protective against breast cancer in humans and in rodents. In humans having a child before the age of 20 decreases risk of breast cancer by half. Using microarray analysis researchers from Basel discovered that genes involved in the immune system and differentiation were up-regulated after pregnancy while the activity of genes coding for growth factors was reduced.
The activity of one particular gene Wnt4 was also down-regulated after pregnancy. The protein from this gene (Wnt4) is a feminising protein -- absence of this protein propels a fetus towards developing as a boy. Wnt and Notch are opposing components of a system which controls cellular fate within an organism and when the team looked at Notch they found that genes regulated by notch were up-regulated, Notch-stimulating proteins up-regulated and Notch-inhibiting proteins down-regulated.
Wnt/Notch signalling ratio was permanently altered in the basal stem/progenitor cells of mammary tissue of mice by pregnancy. Mohamed Bentires-Alj from the Friedrich Miescher Institute for Biomedical Research, who led this study explained, "The down-regulation of Wnt is the opposite of that seen in many cancers, and this tightened control of Wnt/Notch after pregnancy may be preventing the runaway growth present in cancer."
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The above story is reprinted from materials provided by BioMed Central.
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Journal Reference:
- Fabienne Meier-Abt, Emanuela Milani, Tim Roloff, Heike Brinkhaus, Stephan Duss, Dominique S Meyer, Ina Klebba, Piotr J Balwierz, Erik van Nimwegen and Mohamed Bentires-Alj. Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium. Breast Cancer Research, 2013 (in press) [link]
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/M01wkIKwjeM/130428230427.htm
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রবিবার, ২৮ এপ্রিল, ২০১৩
Leftist priests: Francis can fix church 'in ruins'
BUENOS AIRES, Argentina (AP) ? A new pope from Latin America known for ministering to the poor in his country's slums is raising the hopes of advocates of liberation theology, whose leftist social activism had alarmed previous pontiffs.
Prominent liberation theologian Leonardo Boff said Pope Francis has what it takes to fix a church "in ruins" and shares his movement's commitment to building a church for the world's poor.
"With this pope, a Jesuit and a pope from the Third World, we can breathe happiness," Boff said Saturday at a Buenos Aires book fair. "Pope Francis has both the vigor and tenderness that we need to create a new spiritual world."
The 74-year-old Brazilian theologian was pressured to remain silent by previous popes who tried to draw a hard line between socially active priests and leftist politics. As Argentina's leading cardinal before he became pope, Francis reinforced this line, suggesting in 2010 that reading the Gospel with a Marxist interpretation only gets priests in trouble.
But Boff says the label of a closed-minded conservative simply doesn't fit Francis.
"Pope Francis comes with the perspective that many of us in Latin America share. In our churches we do not just discuss theological theories, like in European churches. Our churches work together to support universal causes, causes like human rights, from the perspective of the poor, the destiny of humanity that is suffering, services for people living on the margins."
The liberation theology movement, which seeks to free lives as well as souls, emerged in the 1960s and quickly spread, especially in Latin America. Priests and church laypeople became deeply involved in human rights and social struggles. Some were caught up in clashes between repressive governments and rebels, sometimes at the cost of their lives.
The movement's martyrs include El Salvador's Archbishop Oscar Romero, whose increasing criticism of his country's military-run government provoked his assassination as he was saying Mass in 1980. He was killed by thugs connected to the military hierarchy a day after he preached that "no soldier is obliged to obey an order that is contrary to the will of God." His killing presaged a civil war that killed nearly 90,000 over the next 12 years.
The case for beatification of Romero languished under popes John Paul II and Benedict XVI due to their opposition to liberation theology, but he was put back on track to becoming a saint days after Francis became pope.
Scores of other liberation theologians were killed in the 1970s and 1980s. Six Jesuit teachers were slaughtered at their university in El Salvador in 1989. Other priests and lay workers were tortured and vanished in the prisons of Chile and Argentina. Some were shot to death while demanding land rights for the poor in Brazil. A handful went further and picked up arms, or died accompanying rebel columns as chaplains, such as American Jesuit James Carney, who died in Honduras in 1983.
While even John Paul embraced the "preferential option for the poor" at the heart of the movement, most church leaders were unhappy to see intellectuals mixing doses of Marxism and class struggle into their analysis of the Gospel. It was a powerfully attractive mixture for idealistic Latin Americans who were raised in Catholic doctrine, educated by the region's army of Marxist-influenced teachers, and outraged by the hunger, inequality and bloody repression all around them.
In the late 1960s and early 1970s, hundreds of Argentine priests were affiliated with a movement that proclaimed Christian teaching "inescapably obliges us to join in the revolutionary process for urgent radical change of existing structures and to reject formally the capitalistic system we see around us ... We shall go forward in search of a Latin American brand of socialism that will hasten the coming of the new man."
John Paul and his chief theologian, Cardinal Joseph Ratzinger, drove some of the most ardent and experimental liberation theologians out of the priesthood, castigated some of those who remained, and ensured that the bishops and cardinals they promoted took a wary view of leftist social activism.
Yet much of the movement remained, practiced by thousands of grassroots "base communities" working out of local parishes across the hemisphere, nurtured by nuns, priests and a few bishops who put freedom from hunger, poverty and social injustice at the heart of the Church's spiritual mission.
Hundreds of advocates at a conference in Brazil last year declared themselves ready for a comeback.
"At times embers are hidden beneath the ashes," said the meeting's final declaration, which expressed hopes of stirring ablaze "a fire that lights other fires in the church and in society."
Boff and other advocates are thrilled that this new pope spent so much time ministering in the slums, and are inspired by his writings, which see no heresy in social action.
"The option for the poor comes from the first centuries of Christianity. It is the Gospel itself," said then-Cardinal Jorge Mario Bergoglio during a 2010 deposition in a human rights trial. He said that if he were to repeat "any of the sermons from the first fathers of the church, from the 2nd or 3rd century, about how the poor must be treated, they would say that mine would be Maoist or Trotskyite."
Msgr. Gregorio Rosa Chavez, the auxiliary bishop of San Salvador, said Romero and Francis have the same vision of the church. "When he says 'a church that is poor and for the poor,' that is what Monsignor Romero said so many times," he said.
Rosa Chavez said neither was among the most radical of churchmen.
"There are many theologies of liberation," he said. "The pope represents one of these currents, the most pastoral current, the current that combines action with teaching." He described Francis' version as "theologians on foot, who walk with the people and combine reflection with action," and contrasted them with "theologians of the desk, who are from university classrooms."
John Paul II himself embraced the term "liberation theology," but was also credited with inspiring resistance to the communist regime in his native Poland, and was allergic to socialist pieties.
For 30 years, the Vatican has been seeding Latin America, Africa and Asia with cardinals "who have tended to be, adverse, to put it kindly, to liberation theology," said Stacey Floyd-Thomas, a professor of ethics and society at Vanderbilt University Divinity School.
In Brazil, Sao Paulo Archbishop Odilo Scherer, widely considered a possible pope, told the Estado de S. Paulo newspaper last year that liberation theology "lost its reason of being because of its Marxist ideological underpinnings . which are incompatible with Christian theology."
"It had its merits by helping bring back into focus matters like social justice, international justice and the liberation of oppressed peoples. But these were always constant themes in the teachings of the Church," Scherer said.
In 1984, Ratzinger put Boff in Galileo's chair for a Vatican inquisition over his writings, eventually stripping him of his church functions and ordering him to spend a year in "obedient silence." Nearly a decade later, in 1993, the Vatican pressured him again, and he quit the Franciscan order.
Now Boff says Francis has brought a "new spring" to the global church.
"Josef Ratzinger. He was against the cause of the poor, liberation theology," Boff said. "But this is from last century. Now we are under a new pope."
___
Associated Press Writers Michael Warren in Buenos Aires, Jenny Barchfield in Rio de Janeiro, Marcos Aleman in San Salvador and John Rice in Mexico City contributed to this report.
Source: http://news.yahoo.com/leftist-priests-francis-fix-church-ruins-213627659.html
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Italian policemen shot near new gov't swearing-in
ROME (AP) ? In the very moments Italy's new coalition government was being sworn in, ending months of political paralysis in a country hoping to revive a bleak economy, a middle-aged unemployed bricklayer opened fire Sunday in the square outside the premier's office, seriously wounding two policemen, authorities said.
The alleged gunman from Calabria, a southern region plagued by joblessness and organized crime, told investigators he wanted to shoot politicians. But finding none in the square, he instead shot at Carabinieri paramilitary police.
A bullet pierced one of the policemen in the neck, passing through his spinal column, doctors said, adding it wasn't yet known if the 50-year-old officer would have any paralysis. The other one was shot in the leg and suffered a fracture.
The newly sworn in interior minister, Angelino Alfano, said a preliminary investigation indicated the shooting, which also slightly injured a pregnant bystander, amounted to a "tragic criminal gesture of a 49-year-old unemployed" man.
But the shooting was also a violent expression of social tensions in Italy, where unemployment is soaring, an increasing number of businesses are shutting their doors permanently and new political corruption scandals make headlines nearly every day.
Politicians described the attack as a disturbing call to fix Italy's economy.
"From what we understand, it's mainly personal problems, work, personal debts" that fueled the gunman's attack, said Guglielmo Epifani, a top official in Premier Enrico Letta's center-left Democratic Party.
Epifani said in a state TV interview that while the financial crisis has caused some to commit suicide, "this is the first time someone shoots to kill" someone else "in a place filled with innocent people."
"The symbolism is there," he said. The political world "must highlight its responsibility during the crisis before the country," he said.
In brief comments to reporters after paying a hospital visit to the more seriously wounded policeman, Letta said, "it is a moment in which each must do one's own duty."
The 46-year-old Letta will speak to Parliament on Monday, laying out his strategy to reduce joblessness while still sticking to the austerity measures needed to keep the eurozone's No. 3 economy from descending into a sovereign debt crisis. He will then face confidence votes needed to confirm his government.
Prosecutors identified the gunman as Luigi Preiti. Jobless, with a broken marriage and reportedly burdened by gambling debts he couldn't pay, Preiti had recently returned from Italy's affluent north, where he could no longer find work. He moved into his parents' home in Rosarno, a bleak Calabrian farm town where unemployment was already endemic before the last years of stagnation and recession sent youth unemployment soaring to nearly 40 percent nationwide.
His intended target was politicians, but with none in the square, he shot at the Carabinieri paramilitary police, Rome Prosecutor Pierfilippo Laviani told reporters, citing what he said Preiti told him when he questioned him.
Preiti, who was taken to the hospital for bruises, confessed to the shooting and didn't appear mentally unbalanced, Laviani said.
"He is a man full of problems, who lost his job, who lost everything," the prosecutor said. "He was desperate."
Mired in recession and suffering from soaring unemployment, Italy had been in political deadlock since an inconclusive February election. Social and political tensions have been running high among voters divided among a center-left bloc, conservative parties and an anti-establishment protest movement, which capitalized on public disgust with politicians to become Parliament's No. 3 force in its first national election bid.
The leader of the protest 5 Star Movement, comedian-turned-politician Beppe Grillo, has been criticized for inflammatory statements in the past, including saying during a campaign rally that the Parliament building could be a bombing target. He incessantly derides mainstream politicians as the root of Italy's ills.
"Words thrown like stones can become bullets," Rome's right-wing mayor, Gianni Alemanno, said after the shooting.
Grillo swiftly moved to distance what he describes as a grass-roots political movement from any calls to violence.
"The movement isn't at all violent," Grillo said.
Sunday was supposed to be a hopeful day with a new government, which, only a day earlier, was forged out of two bitter political enemies. Letta's forces, with strong roots in a former Communist party as well as centrist Christian Democrats, and media mogul Silvio Berlusconi's center-right bloc had agreed after days of negotiations to a kind of truce coalition intent on economic, political and electoral reform.
Then the sound of shots pierced the happy chatter in Piazza Colonna, near a busy shopping street shortly just as Letta and his new ministers were taking their oaths at the sumptuous hall of the Quirinal presidential palace, about a kilometer (half mile) away.
Sky TG24 TV and RAI state TV each showed a split screen, on one side, the chaos of panicked people fleeing the square; on the other side, smiling ministers taking the oath of office to work for the good of the nation.
"When I heard the first shot, I turned around and saw a man standing there, some 15 meters (50 feet) away from me. He held his arm out and I saw him fire another five, six shots," AP Television cameraman Fanuel Morelli, who was amazed at what appeared to be the man's deliberate calm, said. "He was firing at the second Carabiniere, who was about 4 meters (13 feet) in front of him."
The gunman was immediately wrestled to the ground by police outside Chigi Palace, which houses the premier's office. The new ministers arrived at the premier's office about 90 minutes later, for their first Cabinet meeting, some of them coming by foot as a way to reassure the public the area was safe.
The shooting panicked tourists and locals in the square on a rare sunny day at the end of a four-day holiday weekend.
A video surveillance camera on the Parliament building caught the attacker on film just before and during the shooting, Italian news reports said. In the film, the shooter is seen walking at a steady pace along a narrow street that leads from near Parliament's lower house to the edge of Colonna Square, where police officers appear to have stopped him to ask where he was going. Shortly after that, the man begins firing, the surveillance camera showed, according to the reports.
Alfano said Preiti wanted to kill himself after the shooting, but ran out of bullets. He said six shots were fired in all. Laviani said the assailant had obtained his weapons on the black market. Sky reported that Preiti had taken a train to Rome from Calabria on Saturday, and that police found his car parked at a southern train station.
The interior minister said security was immediately stepped up near key venues in the Italian capital, but added authorities were not worried about possible related attacks.
"Our initial investigation indicates the incident is due to an isolated gesture, although further investigations are being carried out," he said.
The ministers were kept briefly inside for security reasons until it was clear there was no immediate danger.
Preiti's uncle, interviewed by Sky, said the alleged gunman had moved back to his parents' home in Calabria because he could no longer find work as a bricklayer. "He was a great worker. He could build a house from top to bottom," the uncle, Domenco Preiti, said.
The shooting revived ugly memories of the 1970s and 1980s in Italy, when domestic terrorism plagued the country during a time of high political tension between right-wing and left-wing blocs.
President Barack Obama wished the new Italian government well. The White House press office said Obama was looking forward to working closely with Letta's government "to promote trade, jobs, and growth on both sides of the Atlantic and tackle today's complex security challenges."
There was no direct reference to the shooting in the White House statement.
Trying to renew Italy's largely discredited political class, Letta brought many political newcomers into his Cabinet, including an eye surgeon who is a Congo native, and now is Italy's first black minister, in charge of integration issues involving the growing immigrant population.
But the new premier also sought to reassure European central bankers and EU officials anxious that his government will stay the austerity course set by Mario Monti, who replaced Berlusconi in 2011 to save Italy from sliding deeper into the sovereign debt crisis. Letta picked the Italian central bank's director general, who formerly worked at the International Monetary Fund, to hold the crucial economy ministry.
While the coalition's bitter rival blocs might be enjoying a truce, relations could deteriorate. Berlusconi has insisted that the government's first act should be undoing a highly unpopular property tax Monti established to help the state's coffers.
Source: http://news.yahoo.com/italian-policemen-shot-near-govt-swearing-201756998.html
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How earthquakes in Chile have permanently deformed Earth
Earthquakes can permanently crack the Earth, an investigation of quakes that have rocked Chile over the past million years suggests.
Although earthquakes can wreak havoc on the planet's surface, more than a century of research has suggested the Earth actually mostly rebounds after quakes, with blocks of the world's crust elastically springing back, over the course of months to decades, to the way they initially were. Such rebounding was first seen after investigations of the devastating 1906 San Francisco temblor thathelped lead to the destruction of more than 80 percent of the city. The rebound is well-documented nowadays by satellite-based GPS systems that monitor Earth's movements.
However, structural geologist Richard Allmendinger of Cornell University and his colleagues now find major earthquakes of magnitude 7 or greater apparently caused the crust in northern Chile to crack permanently. [The 10 Biggest Earthquakes in History]
"My graduate students and I originally went to northern Chile to study other features," Allmendinger said. "While we were there, our Chilean colleague, Professor Gabriel Gonz?lez of the Universidad Cat?lica del Norte, took us to a region where these cracks were particularly well-exposed."
"I still remember feeling blown away ? never seen anything like them in my 40 years as a geologist ? and also perplexed," Allmendinger told OurAmazingPlanet. "What were these features and how did they form? Scientists hate leaving things like this unexplained, so it kept bouncing around in my mind."
Atacama exposed
In northern Chile, "the driest place on Earth, we have a virtually unique record of great earthquakes going back a million years," Allmendinger said. Whereas most analyses of ancient earthquakes only probe cycles of two to four quakes, "our record of upper plate cracking spans thousands of earthquake cycles," he noted.
The record of the vast number of earthquakes captured in northern Chilean rocks allowed the researchers to examine their average behavior over a much longer period of time, which makes it easier to pick out any patterns. They discovered that a small but significant 1 to 10 percent of the deformation of the Earth caused by 2,000 to 9,000 major quakes over the past 800,000 to 1 million years was permanent, involving cracks millimeters to meters large in the crust of the Atacama Desert. The crust may behave less elastically than previously thought.
"It is only in a place like the Atacama Desert that these cracks can be observed ? in all other places, surface processes erase them within days or weeks of their formation, but in the Atacama, they are preserved for millions of years," Allmendinger said. "We have every reason to believe that our results would be applicable to other areas, but is simply not preserved for study the way that it is in the Atacama Desert," he added.
Model rethink
This work "calls into question the details of models that geophysicists who study the earthquake cycle use," Allmendinger said. "Their models generally assume that all of the upper-plate deformation related to the earthquake cycle is elastic ? recoverable, like an elastic band ? and not permanent. If some of the deformation is permanent, then the models will have to be rethought and more complicated material behaviors used.
The area the researchers studied, the Iquique Gap, "is one of the few places along western South America that has not had a great earthquake in the last 100 years and thus has a high probability of a major earthquake in the next couple of decades," Allmendinger added. "We may get to test out predictions about earthquakes if the next great earthquake there happens in the next couple of decades."
The scientists detailed their findings online April 28 in the journal Nature Geoscience.
Follow OurAmazingPlanet?@OAPlanet, Facebook?and Google+. Original article at LiveScience's OurAmazingPlanet.
Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.Source: http://news.yahoo.com/earthquakes-chile-permanently-deformed-earth-170116659.html
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Navy Sonar Criticized For Harming Marine Mammals
The U.S. Navy is planning to expand training exercises off California and Hawaii, citing the need for military readiness. That's raising concerns about threatened whales and marine mammals, because sonar is known harm and, in some cases, kill them. The state of California is fighting the Navy's plan.
Source: http://www.npr.org/2013/04/26/179297747/navy-sonar-criticized-for-harming-marine-mammals?ft=1&f=1007
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Investigators push ahead in Boston bombing probe
FILE - This April 25, 2013 file photo shows the mother of the two Boston bombing suspects, Zubeidat Tsarnaeva, left, speaking at a news conference in Makhachkala, the southern Russian province of Dagestan. Two government officials tell The Associated Press that U.S. intelligence agencies added the Boston bombing suspects' mother to a federal terrorism database about 18 months before the attack. At right is her sister-in-law Maryam. (AP Photo/Musa Sadulayev, File)
FILE - This April 25, 2013 file photo shows the mother of the two Boston bombing suspects, Zubeidat Tsarnaeva, left, speaking at a news conference in Makhachkala, the southern Russian province of Dagestan. Two government officials tell The Associated Press that U.S. intelligence agencies added the Boston bombing suspects' mother to a federal terrorism database about 18 months before the attack. At right is her sister-in-law Maryam. (AP Photo/Musa Sadulayev, File)
FILE - This combination of undated file photos shows Tamerlan Tsarnaev, 26, left, and Dzhokhar Tsarnaev, 19. The FBI says the two brothers are the suspects in the Boston Marathon bombing, and are also responsible for killing an MIT police officer, critically injuring a transit officer in a firefight and throwing explosive devices at police during a getaway attempt in a long night of violence that left Tamerlan dead and Dzhokhar captured, late Friday, April 19, 2013. The ethnic Chechen brothers lived in Dagestan, which borders the Chechnya region in southern Russia. They lived near Boston and had been in the U.S. for about a decade, one of their uncles reported said. Since Monday, Boston has experienced five days of fear, beginning with the marathon bombing attack, an intense manhunt and much uncertainty ending in the death of one suspect and the capture of the other. (AP Photo/The Lowell Sun & Robin Young, File)
New York City Police Commissioner Raymond Kelly, left, and Mayor Michael Bloomberg hold a news conference, Thursday, April, 25, 2013 in New York. The two say the Boston Marathon bombing suspects intended to blow up their remaining explosives in Times Square. They said Dzhokhar Tsarnaev told Boston investigators from his hospital bed that he and his brother had discussed going to New York to detonate their remaining explosives. (AP Photo/Mark Lennihan)
This image taken from surveillance video provided by the Boston Regional Intelligence Center shows Boston Marathon bombing suspect Dzhokhar Tsarnaev at a Bank of America ATM in Watertown, Mass. at 11:18 p.m. on April 18, 2013. The next day, police intercepted Dzhokhar and his 26-year-old brother Tamerlan in a blazing gunbattle that the elder brother dead. Dzhokhar, 19, is charged with carrying out the Boston Marathon bombing April 15 that killed three people and wounded more than 260, and he could get the death penalty. (AP Photo/Boston Regional Intelligence Center)
This Friday, April 26, 2013 photo shows the entrance of the Devens Federal Medical Center (FMC) in Devens, Mass. The U.S. Marshals Service said Friday that Dzhokhar Tsarnaev, charged in the April 15, 2013 Boston Marathon bombing, had been moved from a Boston hospital to the federal medical center at Devens, about 40 miles west of the city. (AP Photo/Elise Amendola)
BOSTON (AP) ? With the Boston marathon bombing suspect in a prison hospital, investigators are pushing forward both in the U.S. and abroad to piece together the myriad details of a plot that killed three people and injured more than 260.
FBI agents picked through a landfill near the University of Massachusetts Dartmouth, where 19-year-old suspect, Dzhokhar Tsarnaev, was a sophomore. FBI spokesman Jim Martin would not say what investigators were looking for.
A federal law enforcement official not authorized to speak on the record about the investigation told The Associated Press on the condition of anonymity on Friday that the FBI was gathering evidence regarding "everything imaginable."
Meanwhile, U.S. officials said the bombing suspects' mother had been added to a federal terrorism database about 18 months before the April 15 attack ? a disclosure that deepens the mystery around the Tsarnaev family and marks the first time American authorities have acknowledged that Zubeidat Tsarnaeva was under investigation before the tragedy.
Dzhokhar Tsarnaev is charged with joining with his older brother, Tamerlan Tsarnaev, now dead, in setting off the shrapnel-packed pressure-cooker bombs. The brothers are ethnic Chechens from Russia who came to the United States about a decade ago with their parents.
Investigators have said it appears the brothers were angry about the U.S. wars in Afghanistan and Iraq.
Two government officials, speaking on condition of anonymity because they were not authorized to speak publicly about the investigation, said the CIA had Zubeidat Tsarnaeva's name added to the terror database along with that of her son Tamerlan after Russia contacted the agency in 2011 with concerns that the two were religious militants.
About six months earlier, the FBI investigated mother and son, also at Russia's request, one of the officials said. The FBI found no ties to terrorism. Previously U.S. officials had said only that the FBI investigated Tamerlan Tsarnaev.
In an interview from Russia, Tsarnaeva said Friday that she has never been linked to terrorism.
"It's all lies and hypocrisy," she said from Dagestan. "I'm sick and tired of all this nonsense that they make up about me and my children. People know me as a regular person, and I've never been mixed up in any criminal intentions, especially any linked to terrorism."
Tsarnaeva faces shoplifting charges in the U.S. over the theft of more than $1,624 worth of women's clothing from a Lord & Taylor department store in Natick in 2012.
Earlier this week, she said she has been assured by lawyers that she would not be arrested if she traveled to the U.S., but she said she was still deciding whether to go. The suspects' father, Anzor Tsarnaev, said that he would leave Russia soon for the United States to visit one son and lay the other to rest.
A team of investigators from the U.S. Embassy in Moscow questioned both parents in Russia this week.
Late this week, Dzhohkar Tsarnaev was taken from Beth Israel Deaconess Medical Center, where he was recovering from a throat wound and other injuries suffered during an attempt to elude police, and was transferred to the Federal Medical Center Devens, about 40 miles from Boston, the U.S. Marshals Service said. The facility, at a former Army base, treats federal prisoners.
"It's where he should be; he doesn't need to be here anymore," said Beth Israel patient Linda Zamansky, who thought his absence could reduce stress on bombing victims who have been recovering at the hospital under tight security.
Two college buddies of his ? Azamat Tazhayakov and Dias Kadyrbayev ? have been interviewed at length, twice, by FBI agents and have cooperated fully, said Kadyrbayev's lawyer, Robert Stahl, a former federal prosecutor.
They were detained April 20 after being questioned in connection with the attacks, but are not suspects, Stahl said. They are being detained at a county jail in Boston for violating their student visas by not regularly attending classes, he said.
The two, both students from Kazakhstan, had nothing to do with the attack and had seen no hints that their friend harbored any violent or terrorist sympathies, Stahl said.
Meanwhile, New York's police commissioner said the FBI was too slow to inform the city that the Boston Marathon suspects had been planning to bomb Times Square days after the attack at the race.
Federal investigators learned about the short-lived scheme from a hospitalized Dzhokhar Tsarnaev during a bedside interrogation that began Sunday night and extended into Monday morning, officials said. The information didn't reach the New York Police Department until Wednesday night.
"We did express our concerns over the lag," said police Commissioner Raymond Kelly.
The FBI had no comment Friday.
___
Sullivan reported from Washington. Contributing to this report were Associated Press writers Rodrique Ngowi in Boston, Colleen Long in New York and Ted Bridis, Pete Yost and Julie Pace in Washington.
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American jihadi in Somalia tweets on kill attempt
NAIROBI, Kenya (AP) -- A most-wanted American jihadi in Somalia said Friday that the leader of Islamic extremist rebels in Somali was starting a civil war, just hours after an assassination attempt left the Alabama native with a neck wound.
Omar Hammami posted on Twitter about what he labeled an assassination attempt late Thursday as he was sitting in a tea shop. He posted four pictures, one of which shows his face with blood on his neck and a dark blood-stained t-shirt.
Hammami, one of the two most notorious Americans in overseas jihadi groups, moved from Alabama to Somalia and joined al-Shabab in about 2006. He fought alongside the al-Qaida-linked group for years while gaining fame for posting YouTube videos of jihadi rap songs.
But Hammami had a falling out with al-Shabab and has engaged in a public fight with the group over the last year amid signs of increasing tension between Somalis and foreign fighters in the group. He first expressed fear for his life in an extraordinary web video in March 2012 that publicized his rift with al-Shabab. He said he received another death threat earlier this year that was not carried out.
"Just been shot in neck by shabab assassin. not critical yet," Hammami tweeted late Thursday. On Friday he wrote that the leader of al-Shabab was sending in forces from multiple directions. "we are few but we might get back up. abu zubayr has gone mad. he's starting a civil war," Hammami posted.
Hammami has been a thorn in the side of al-Shabab after accusing the group's leaders of living extravagant lifestyles with the taxes fighters collect from Somali residents. Another Hammami grievance is that the Somali militant leaders sideline foreign militants inside al-Shabab and are concerned only about fighting in Somalia, not globally. Hammami's Friday comment about a civil war could refer to violence between those two groups.
Al-Shabab slapped Hammami publicly in a December Internet statement, saying his video releases are the result of personal grievances that stem from a "narcissistic pursuit of fame." The statement said al-Shabab was morally obligated to stamp out his "obstinacy."
Hammami has enemies on all sides. The U.S. named Hammami to its Most Wanted terrorist list in March and is offering a $5 million reward for information leading to his capture. Al-Shabab fighters are not eligible for the reward.
Along with Adam Gadahn in Pakistan ? a former Osama bin Laden spokesman ? Hammami is one of the two most notorious Americans in jihad groups. He grew up in Daphne, Alabama, a bedroom community of 20,000 outside Mobile. He is the son of a Christian mother and a Syrian-born Muslim father.
Hammami regularly chats on Twitter with a group of American terrorism experts, conversations that are so colloquial and so infused with Americana that many in the counter-terror field have formed a type of digital bond with Hammami.
After Hammami publicized the assassination attempt, one of his Twitter followers, a counter-terrorism expert from Canada, wrote that Hammami had nine lives. Hammami responded with an apparent reference to the movie The Blues Brothers. "'I'm on a mission from God.' minus the blues music," Hammami wrote.
After the shooting, American terrorism expert J.M. Berger, who has a long-running Twitter relationship with Hammami, posted that it looks like Hammami came within a quarter-inch of death. "Perhaps it's time to come in now," Berger tweeted.
Terrorism expert Clint Watts wrote on his blog, Selectedwisdom.com, that the attack proves that Hammami should fear for his life. Watts said Hammami's anti-Shabab social rants were annoying the militant group and he predicted conflict between Somali militants and foreign fighters.
"If there is going to be a war inside Shabaab, I'm guessing it will happen soon," Watts wrote.
Source: http://news.yahoo.com/american-jihadi-somalia-tweets-kill-125412572.html
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Scientists create novel approach to find RNAs involved in long-term memory storage
Scientists create novel approach to find RNAs involved in long-term memory storage
Friday, April 26, 2013Despite decades of research, relatively little is known about the identity of RNA molecules that are transported as part of the molecular process underpinning learning and memory.
Now, working together, scientists from the Florida campus of The Scripps Research Institute (TSRI), Columbia University and the University of Florida, Gainesville, have developed a novel strategy for isolating and characterizing a substantial number of RNAs transported from the cell-body of neuron (nerve cell) to the synapse, the small gap separating neurons that enables cell to cell communication.
Using this new method, the scientists were able to identify nearly 6,000 transcripts (RNA sequences) from the genome of Aplysia, a sea slug widely used in scientific investigation.
The scientists' target is known as the synaptic transcriptome?roughly the complete set of RNA molecules transported from the neuronal cell body to the synapse.
In the study, published recently in the journal Proceedings of the National Academy of Sciences, the scientists focused on the RNA transport complexes that interact with the molecular motor kinesin; kinesin proteins move along filaments known as microtubules in the cell and carry various gene products during the early stage of memory storage.
While neurons use active transport mechanisms such as kinesin to deliver RNA cargos to synapses, once they arrive at their synaptic destination that service stops and is taken over by other, more localized mechanisms?in much the same way that a traveler's bags gets handed off to the hotel doorman once the taxi has dropped them at the entrance.
The scientists identified thousands of these unique sequences of both coding and noncoding RNAs. As it turned out, several of these RNAs play key roles in the maintenance of synaptic function and growth.
The scientists also uncovered several antisense RNAs (paired duplicates that can inhibit gene expression), although what their function at the synapse might be remains unknown.
"Our analyses suggest that the transported RNAs are surprisingly diverse," said Sathya Puthanveettil, a TSRI assistant professor who designed the study. "It also brings up an important question of why so many different RNAs are transported to synapses. One reason may be that they are stored there to be used later to help maintain long-term memories."
The team's new approach offers the advantage of avoiding the dissection of neuronal processes to identify synaptically localized RNAs by focusing on transport complexes instead, Puthanveettil said. This new approach should help in better understanding changes in localized RNAs and their role in local translation as molecular substrates, not only in memory storage, but also in a variety of other physiological conditions, including development.
"New protein synthesis is a prerequisite for maintaining long term memory," he said, "but you don't need this kind of transport forever, so it raises many questions that we want to answer. What molecules need to be synthesized to maintain memory? How long is this collection of RNAs stored? What localized mechanisms come into play for memory maintenance?"
###
In addition to Puthanveettil, who was the first author of the study, authors of "A Strategy to Capture and Characterize the Synaptic Transcriptome," include Igor Antonov, Sergey Kalchikov, Priyamvada Rajasethupathy, Yun-Beom Choi, Maxime Kinet, Irina Morozova, James J. Russo, and Jingyue Ju of Columbia University; Kevin A. Karl of the Howard Hughes Medical Institute; and Eric R. Kandel of Columbia University, the Howard Hughes Medical Institute and the Kavli Institute for Brain Science; and Andrea B. Kohn, Mathew Citarella, Fahong Yu and Leonid L. Moroz of the University of Florida, Gainesville. For more information, see http://www.pnas.org/content/early/2013/04/10/1304422110.long
Scripps Research Institute: http://www.scripps.edu
Thanks to Scripps Research Institute for this article.
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Clipr sends pasted text to your phone via SMS with a press of a button
If you've ever wanted to send some text from your computer to your phone, you usually have to go with a dedicated app like Evernote, with a mobile app required at the other end. With the new version of Clipr for Mac, however, all you need to do is enter your phone number in the settings and the info will magically appear on your mobile device via SMS -- just press the command key when selecting a clip and away it'll go. Right now all major US carriers are supported, with the promise of more to come. For the uninitiated, Clipr is a clipboard manager that works with your computer's existing copy and paste system without any special key combos. Bear in mind that while the app itself is free, the aforementioned SMS feature costs $0.99 extra. Still, at least this particular clip-inspired helper looks to be a lot better than, you know, that other one.
Filed under: Software, Mobile, Apple
Source: Clipr (Mac App Store)
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/gPtU3t3mcHE/
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