শনিবার, ৪ মে, ২০১৩

Pacers finish off Hawks, win Game 6 81-73

ATLANTA (AP) ? The Indiana Pacers packed for an extended trip.

Good call.

George Hill and David West each scored 21 points and the Pacers withstood a furious Atlanta comeback in the fourth quarter, beating the Hawks 81-73 on Friday night to close out the opening-round playoff series four games to two.

After snapping a 13-game losing streak in Atlanta dating to December 2006, Indiana headed off to New York to take on the Knicks in the first two games of the conference semifinals. The opener is Sunday at Madison Square Garden, an itinerary the Pacers prepared for by packing for a possible six days on the road.

"Quick turnaround," said Indiana's Roy Hibbert, who led a dominating Pacers performance on the boards. "Enjoy tonight on the plane ride, get to New York, get something good in our bellies if stuff is still open."

New York finished off the Celtics 88-80 shortly after the horn sounded at Philips Arena. The Pacers were certainly glad they didn't have to return to Indianapolis for a decisive game against the Hawks.

"It's nice to be able to get it done here," Hibbert said. "We showed a lot of resolve when the other team made their run."

The home team had won every game until the Hawks returned to Atlanta and set a franchise playoff record with just nine points in the second quarter on 1-of-15 shooting. The defense broke down in the third, allowing Hill and West to combine for 22 points, and the Pacers built a 65-50 lead going to the fourth.

To their credit, the Hawks showed plenty of heart, slicing Indiana's lead to 76-73 on Al Horford's dunk with 2:13 remaining.

But the comeback fizzled. Atlanta didn't score again, setting up what figures to be a tumultuous offseason.

The Hawks have only three players who are definitely under contract for next season ? Horford is the lone starter in the group ? and it seems likely this will be a much different team next season. Plus, they very well could have a new coach. Larry Drew was in the final year of his contract, and general manager Danny Ferry figures to want his own man in the post as he heads to his second season.

Longtime stalwart Josh Smith, an Atlanta native who has played for the team ever since he was drafted out of high school eight seasons ago, is among those heading into free agency.

"There's plenty of time to think about what the future presents," Smith said. "I'm not really concerned about that right now."

If that's it for Smith in Atlanta, he missed his final shot.

How fitting on a night when the Hawks made only 26 of 78 (33 percent). Horford led with 15 points, while Smith and Devin Harris finished with 14.

Indiana bullied the Hawks much of the game, overcoming their own poor shooting (32 of 76) by bullying Atlanta in the lane. The Pacers finished with a staggering 53-35 lead on the boards.

Hibbert added 17 points and 11 rebounds. Lance Stephenson also had 11 rebounds.

Over the final two games of the series, the Pacers absolutely manhandled the Hawks on the glass, piling up a 104-63 rebounding edge.

"I'm very proud of our guys to come in here, a tough place to win," coach Frank Vogel said. "A particularly tough place for us to win. It's good to end that streak. But more importantly, it's good to advance and show the type of toughness you need to make a deep playoff run. To win with defense and rebounding, that's been our identity all year, and that was the key to the last two victories."

The Hawks went through an absolutely brutal stretch from early in the second quarter to nearly midway through the third, in which they did not actually put the ball in the hoop.

In the equivalent of more than a quarter ? 15:43 to be exact ? Atlanta went 1 of 21 from the field, the only basket awarded to Harris on a goaltending call against Hibbert.

At a time when the Hawks needed one of their best performances of the season, they produced one of their worst.

"I wouldn't have believed it," Smith said. "We just couldn't get it going offensively."

The Hawks couldn't play much worse than they did in the second quarter. They showed little energy. They put up some truly awful shots. They missed even when they got a decent look.

Kyle Korver made the Hawks' only basket of the period on a jumper with 10:35 left. After that, they missed their last 13 shots before heading to the locker room to a round of boos from the home crowd.

If not for Indiana having their own offensive issues ? the Pacers made only 36.6 percent (15 of 41) ? the game would've been a blowout. As it was, the Hawks trailed just 37-29.

Perhaps the most telling sequence for both teams came late in the second. Jeff Teague fumbled away the ball out near the top of the key without being challenged. Indiana's D.J. Augustin took off the other way on an apparent layup, but only to throw up a wild shot that struck the bottom of the backboard. The Hawks followed up with such a pathetic offensive set that 7-footer Johan Petro wound up shooting a 3-pointer just ahead of the shot clocked.

It missed.

So did just about everything else the Hawks put up in the first half.

Atlanta's offensive woes shifted to the defensive end in the third quarter. The Hawks continually got lost on switches, at one point leaving Hill totally alone on a 3-pointer. He knocked down the shot and Harris looked around, his arms in the air wondering what was happening to his team.

The Hawks showed some resilience in their final quarter of the season.

But they expended so much energy wiping out a deficit that had been as high as 19 points, there was nothing left at the end. Horford's rim-hanging dunk was their final basket.

While clearly seeming to sense his three-year run in Atlanta is over, Drew said he was proud of a team that many felt would have trouble making the playoffs after trading away All-Star Joe Johnson and bringing in a bunch of guys in the final year of their contracts.

Even the coach knew he was a lame duck, having the option on his contact picked up last summer but not getting an extension.

"I'm really, really proud of my group," said Drew, who has led the Hawks to three straight playoff appearances but was eliminated in the first round the last two years. "When you've got 11 or 12 guys on one-year deals, and the coach is in his last year, it could've gone either way. But we hung in there and stuck with it."

Notes: Atlanta G Teague has an awful finish to the series, going 3 of 16 in Game 5, and 3 of 12 in the deciding contest. ... Hibbert had his first double-double of the series. ... The Hawks finally shot well from the free-throw line (18 of 20) after struggling much of the series. Unfortunately, they couldn't score consistently from anywhere else. ... Hawks F Ivan Johnson was whistled for a technical for the second game in a row. Indiana's Jeff Pendergraph also picked up a T.

___

Follow Paul Newberry on Twitter at www.twitter.com/pnewberry1963

Source: http://news.yahoo.com/pacers-finish-off-hawks-win-game-6-81-014040906.html

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শুক্রবার, ৩ মে, ২০১৩

Scientists create genetically altered mice to model human disease

Friday, May 3, 2013

Whitehead Institute Founding Member Rudolf Jaenisch, who helped transform the study of genetics by creating the first transgenic mouse in 1974, is again revolutionizing how genetically altered animal models are created and perhaps even redefining what species may serve as models.

"This new method is a game changer," says Jaenisch, who is also a professor of biology at MIT. "We can now make a mouse with five mutations in just three to four weeks, whereas the conventional way would take three to four years. And it's rather straightforward, probably even easier than the conventional way."

Scientists create models in mice by altering specific genes that have been associated with a given disease. The models allow for the study of the development and course of the disease and the effects of various interventions, including genetic and chemical. For the past 20 years, the creation of such models has remained relatively unchanged: scientists insert a piece of DNA into a mouse embryonic stem (ES) cell, inject the modified cell into a very early-stage embryo, called a blastocyst, then implant this developing ball of cells into a foster female mouse. The whole process can take years and tens of thousands of dollars to establish a mouse strain with, for example, a single copy of a gene "knocked out". Such knockouts can only be created in very few species, including mice and rats, whose ES cells can be grown and modified reliably.

The new approach used by scientists in Jaenisch's lab bypasses ES cells to quickly and efficiently produce mice with mutations in both copies of multiple genes. In next week's issue of the journal Cell, Haoyi Wang, Hui Yang, and Chikdu Shivalila describe their technique, which is based on a system that certain bacteria use to fend off viral attacks.

This is the first time that the system, known as CRISPR (for "clustered regularly interspaced short palindromic repeat")/Cas (for "CRISPR-associated"), has been used to alter multiple genes in a single multicellular organism. Shivalila says the process is so accessible that he expects other labs to adopt it quickly.

"For any institution or university with a core facility, we think this will be the way they will start making mice carrying specific mutations because it's a lot faster and so efficient," says Shivalila, one of Jaenisch's graduate students. "We were surprised that we could get two genes 'knocked out' at four loci very, very efficiently, about 80% efficiency. If we used TALENs, a more recent and complicated development in genetic engineering, we got 30% efficiency for just one gene."

Because the CRISPR/Cas technique can generate mutant mice even without using ES cells, a limitation of the conventional method for making models, genetic research may no longer be confined to a limited list of model organisms?those for which ES cells exist.

"This breaks down the definition of model organism," says Wang, a postdoctoral researcher in Jaenisch's lab. "So now, even with limited resources, any animal with established embryo manipulation procedures could be the subject of genome engineering. With many of the animals' genomes that have been sequenced, we could use this technology to establish efficient genetic manipulations in more species, to study the unique biology of each, and to learn more about evolution."

Thus, Wang, Yang, and Shivalila have used CRISPR/Cas to create mouse models only, but the team is excited broaden its application to other animals.

"We also need to see if the CRISPR/Cas system has any unexpected, undesired off-target effects, changes to the genome that we don't want," says Yang, a postdoctoral researcher in the Jaenisch lab. "So we need study this further to establish the fidelity of the system. But I think this will be the way to go."

###

"One-step generation of mice carrying mutations in multiple genes by CRISPR-Cas mediated genome engineering"

Cell, May 9, 2013

Whitehead Institute for Biomedical Research: http://www.wi.mit.edu/index.html

Thanks to Whitehead Institute for Biomedical Research for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/128114/Scientists_create_genetically_altered_mice_to_model_human_disease

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Real estate website fraud becomes issue | HousingWire

5/2/13 4:02pm

Ron Bailey, a Pocono Lake, Pa.-based broker, recently learned that a scammer scraped his Zillow rental listing and reposted it at a lower rent on Zillow, where the original listing already was.?After hearing from a potential renter, the scammer corresponded through email with her, using Bailey?s name, an email address with Bailey?s name in it, and a phone number bearing Bailey?s area code, writes Inman.

The chairman of the Pocono Mountains Association of Realtors? MLS, Malcolm Waring said he's?been assured that they?re going to beef up fraud prevention. But, he added, if he learns of a similar scam perpetrated on Zillow ($60.17 0%) or HotPads again, "it?s going to be the last time."

Source: http://www.housingwire.com/fastnews/2013/05/02/real-estate-website-fraud-becomes-issue

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Telling time on Saturn: Undergraduate student shows how planet's magnetosphere changes with the seasons

May 3, 2013 ? A University of Iowa undergraduate student has discovered that a process occurring in Saturn's magnetosphere is linked to the planet's seasons and changes with them, a finding that helps clarify the length of a Saturn day and could alter our understanding of Earth's magnetosphere.

Saturn's magnetosphere is the third largest structure in the solar system, eclipsed only by the magnetic fields of the sun and Jupiter. Unlike Earth, which has a visible rocky surface and rotates once every 24 hours, Saturn is composed mostly of clouds and liquid gas layers, each rotating about the planet at its own rate of speed. This variation in rotation made it difficult for scientists to pin down time for the planet.

Decades ago, a strong and naturally occurring radio signal, called Saturn kilometric radiation (SKR), was believed to give an accurate measurement of a Saturn day. But data gathered by an ESA/NASA spacecraft proved otherwise.

Now, using data from NASA's Cassini spacecraft, which entered orbit around Saturn in 2004, UI space physicist Donald Gurnett and other scientists showed that the north and south poles have their own SKR "days" that vary over periods of weeks and years. How these different periods arise and are driven through the magnetosphere has become a central question of the Cassini mission, according to NASA officials.

The discovery by Tim Kennelly, a UI junior majoring in physics and astronomy, is one of the first direct observations of seasonal changes in Saturn's magnetosphere. In addition, the finding carries over to all planets having a magnetosphere, including Earth.

"I'm pleased to have contributed to our understanding of Saturn's magnetosphere so early in my career," says Kennelly, the lead author of the paper published online in the American Geophysical Union's (AGU) Journal of Geophysical Research. "I hope this trend continues."

Scientists have known for some time that Saturn's magnetospheric processes are linked together, from the activity generating the SKR emission relatively near the planet to the periodic signatures in Saturn's magnetosphere stretching millions of miles downstream in the planet's magnetotail. But they didn't know how they were linked.

Kennelly analyzed phenomena recorded between July 2004 and December 2011 by Cassini's UI-built Radio and Plasma Wave Science (RPWS) instrument and came to some novel conclusions about how the events are linked. First, he looked at inward-moving "flux tubes" composed of hot, electrically charged gas, called plasma. Focusing on the tubes when they initially formed and before they had a chance to dissipate under the influence of the magnetosphere, he found that the occurrence of the tubes correlates with activity in the northern and southern hemisphere depending upon the season.

Kennelly found that during winter in the northern hemisphere, the occurrence of flux tubes correlates with SKR period originating in the northern hemisphere. A similar flux tube and SKR correlation was noted for the southern hemisphere during southern winter. The events are strongly ordered, he says, and follow Saturn's seasonal changes.

This finding may alter how scientists look at Earth's magnetosphere and the Van Allen radiation belts that affect a variety of activities at Earth ranging from space flight safety to satellite and cell phone communications.

Commenting on his research experience, Kennelly says, "I'm really happy with the support I've received from Don Gurnett's group. They let me do a lot of the research on my own. I'm really appreciative." He adds that he will begin applying to graduate schools next semester and plans to earn his doctorate in plasma physics.

In addition to Kennelly, UI researchers include UI postdoctoral scholar Jared Leisner, associate research scientist George Hospodarsky and Donald Gurnett, head of the RPWS instrument investigation and the James A. Van Allen/Roy J. and Lucille A. Carver Professor of Physics and Astronomy.

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Story Source:

The above story is reprinted from materials provided by University of Iowa. The original article was written by Gary Galluzzo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. T. J. Kennelly, J. S. Leisner, G. B. Hospodarsky, D. A. Gurnett. Ordering of injection events within Saturnian SLS longitude and local time. Journal of Geophysical Research: Space Physics, 2013; 118 (2): 832 DOI: 10.1002/jgra.50152

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/jruyssL9gf4/130503094951.htm

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When state law conflicts with the EEOC on criminal background ...

Last year, the EEOC issued its long awaited Enforcement Guidance on the Consideration of Arrest and Conviction Records in Employment Decisions under Title VII. While the Guidance was much more fair and balanced than many employer advocates (me included) expected, it does include some head-scratchers for businesses. One such conundrum is how regulated employers are supposed to act when across-the-board criminal background searches are required by state law, as the EEOC takes the position that a blanket requirement violates Title VII.

Per the EEOC:

States and local jurisdictions also have laws and/or regulations that restrict or prohibit the employment of individuals with records of certain criminal conduct. Unlike federal laws or regulations, however, state and local laws or regulations are preempted by Title VII if they ?purport[] to require or permit the doing of any act which would be an unlawful employment practice? under Title VII. Therefore, if an employer?s exclusionary policy or practice is not job related and consistent with business necessity, the fact that it was adopted to comply with a state or local law or regulation does not shield the employer from Title VII liability.

How is an employer supposed to handle this conflict? Waldon v. Cincinnati Public Schools, currently pending in the Southern District of Ohio, may provide some future guidance. That case concerns the application of Ohio H.B. 190, which became law in 2007. That law requires criminal background checks of all current school employees, regardless of whether their duties involve the care, custody, or control of children, and mandates the termination of any employee with a certain number of historical convictions, regardless of the convictions' age.

Two African-American employees challenge that H.B. 190 has an unlawful disparate impact because of race. Both were terminated based on decades-old convictions. All told, the Cincinnati Public Schools fired 10 employees as a result of background checks conducted pursuant to H.B. 190; nine of the 10 fired were African-American.

In is early in the litigation of the Waldon case. The court denied the employer's motion to dismiss.

First, it concluded that it was clear that the Plaintiffs pleaded a prima facie case of disparate impact.

Although there appears to be no question that Defendant did not intend to discriminate, intent is irrelevant and the practice that it implemented allegedly had a greater impact on African-Americans than others.

The existence of statistically significant disparate impact, however, if only the first step in the analysis. An employer can avoid liability if the challenged practice is justified by business necessity. While the court believed this issue to be "a close call," it ultimately concluded that it could not make that call on a motion to dismiss:

Obviously the policy as applied to serious recent crimes addressed a level of risk the Defendant was justified in managing due to the nature of its employees' proximity to children. However, in relation to the two Plaintiffs in this case, the policy operated to bar employment when their offenses were remote in time, when Plaintiff Britton's offense was insubstantial, and when both had demonstrated decades of good performance. These Plaintiffs posed no obvious risk due to their past convictions, but rather, were valuable and respected employees, who merited a second chance.? Under these circumstances, the Court cannot conclude as a matter of law that Defendant's policy constituted a business necessity.

Talk about a tough position in which to place an employer. Does the employer violate state law or violate Title VII? Ultimately, I think the correct answer should be neither. Shouldn't the need to follow state law provide the employer's "business necessity?" If not, employers will be faced in the untenable position of following one law and violating the other.

[photo credit: kevin dooley via photopin cc]

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Anti-EU party shakes British PM's Conservatives in local vote

May 1 (Reuters) - Post position for Saturday's 139th Kentucky Derby at Churchill Downs after Wednesday's draw (listed as barrier, HORSE, jockey, trainer) 1. BLACK ONYX, Joe Bravo, Kelly Breen 2. OXBOW, Gary Stevens, D. Wayne Lukas 3. REVOLUTIONARY, Calvin Borel, Todd Pletcher 4. GOLDEN SOUL, Robby Albarado, Dallas Stewart 5. NORMANDY INVASION, Javier Castellano, Chad Brown 6. MYLUTE, Rosie Napravnik, Tom Amoss 7. GIANT FINISH, Jose Espinoza, Tony Dutrow 8. GOLDENCENTS, Kevin Krigger, Doug O'Neill 9. OVERANALYZE, Rafael Bejarano, Todd Pletcher 10. PALACE MALICE, Mike Smith, Todd Pletcher 11. ...

Source: http://news.yahoo.com/anti-eu-group-beats-british-pms-party-third-012022094.html

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Scientists Are Making Oysters Safe to Eat With Electron Beams

You know what's a turn on? Oysters. You know what's a turn off? Vomit. Oysters might be a delicious aphrodisiac, but they have a tendency to be pretty unsanitary and they can make you sick. But researchers at Texas A&M University have found a way pasteurize the bivalves using electron beams, getting rid of some of the stuff that causes you to upchuck.

Read more...

    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/q0qOr3GOFT4/scientists-are-making-oysters-safe-to-eat-with-electron-486364916

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Traktor DJ gets remixed for iPhone, brings big features to small pockets (video)

Traktor DJ gets remixed for iPhone

Traktor DJ for iPad showed us what can be done when you resist the urge to simply shrink your existing software or just slide it under a touch interface. Since its iOS debut, the folk at Native Instruments have spent the last couple of months cautiously considering how best to transplant the same waveform-based interface over to the iPhone. Today, you can find out. You get everything you find in the iPad version, like three band EQ, filters, hot cues and effects --along with the same key, tempo and timbre matching utilities, plus library sharing with the full-fat desktop version. The UI isn't the only thing getting downsized, either: this iPhone-friendly version costs just $4.99 (compared to $20 on the iPad). That should leave enough change to drop a few on party rock anthems.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/SjuRFbMIGEs/

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বৃহস্পতিবার, ২ মে, ২০১৩

Boeing loses five 747 orders, gains 777 order

May 1 (Reuters) - Post position for Saturday's 139th Kentucky Derby at Churchill Downs after Wednesday's draw (listed as barrier, HORSE, jockey, trainer) 1. BLACK ONYX, Joe Bravo, Kelly Breen 2. OXBOW, Gary Stevens, D. Wayne Lukas 3. REVOLUTIONARY, Calvin Borel, Todd Pletcher 4. GOLDEN SOUL, Robby Albarado, Dallas Stewart 5. NORMANDY INVASION, Javier Castellano, Chad Brown 6. MYLUTE, Rosie Napravnik, Tom Amoss 7. GIANT FINISH, Jose Espinoza, Tony Dutrow 8. GOLDENCENTS, Kevin Krigger, Doug O'Neill 9. OVERANALYZE, Rafael Bejarano, Todd Pletcher 10. PALACE MALICE, Mike Smith, Todd Pletcher 11. ...

Source: http://news.yahoo.com/boeing-loses-five-747-orders-gains-777-order-154350620.html

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The biology behind binge eating

May 1, 2013 ? Female rats are much more likely to binge eat than male rats, according to new research that provides some of the strongest evidence yet that biology plays a role in eating disorders.

The study, by Michigan State University scientists, is the first to establish sex differences in rates of binge eating in animals and has implications for humans. Binge eating is one of the core symptoms of most eating disorders, including bulimia nervosa and the binge/purge subtype of anorexia nervosa, and females are four to 10 times more likely than males to have an eating disorder.

"Most theories of why eating disorders are so much more prevalent in females than males focus on the increased cultural and psychological pressure that girls and women face," said Kelly Klump, lead author and professor of psychology. "But this study suggests that biological factors likely contribute as well, since female rats do not experience the psychosocial pressures that humans do, such as pressures to be thin."

Klump and colleagues ran a feeding experiment with 30 female and 30 male rats over a two-week period, replacing the rodents' food pellets periodically with vanilla frosting. They found that the rate of binge eating "proneness" (i.e., the tendency to consume the highest amount of frosting across all feeding tests) was up to six times higher in female as compared to male rats.

The tendency to binge eat may be related to the brain's natural reward system, or the extent to which someone likes and seeks reward, Klump said. The MSU researchers currently are testing the rats to see if female brains are more sensitive and/or responsive to rewarding stimuli (e.g., high-fat, high-sugar food) and the chemicals that trigger reward behavior.

The answers could ultimately help improve therapy -- both counseling and medications -- for those with eating disorders.

"This research suggests there is probably a biological difference between males and females that we need to explore to understand risk factors and mechanisms," Klump said.

The study is published online in the International Journal of Eating Disorders. Klump's co-authors are Cheryl Sisk, psychology professor, and graduate students Sarah Racine and Britny Hildebrandt.

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Story Source:

The above story is reprinted from materials provided by Michigan State University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Kelly L. Klump, Sarah Racine, Britny Hildebrandt, Cheryl L. Sisk. Sex differences in binge eating patterns in male and female adult rats. International Journal of Eating Disorders, 2013; DOI: 10.1002/eat.22139

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/ccUxlKfnpzc/130501101304.htm

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Girls With Autism May Need Different Treatments Than Boys - Health ...

sadgirl Girls With Autism May Need Different Treatments Than Boys

By Serena Gordon
HealthDay Reporter

WEDNESDAY, May 1 (HealthDay News) ? With four to five times more males affected by autism spectrum disorders than females, much less is known about girls with autism.

Fortunately, more research is beginning to focus on autism in girls, said Geraldine Dawson, chief science officer of Autism Speaks, with two such studies set to be presented Saturday at the International Meeting for Autism Research in San Sebastian, Spain.

?Autism affects boys much more frequently than girls. But, we may be missing some girls. The diagnostic criteria were developed using symptoms in boys, and symptoms in girls and boys may be different,? Dawson explained.

?Because of this difference in incidence, researchers may end up with a small number of girls in studies,? she said, adding that differences in symptoms or reactions to treatments may lead to the girls? data being excluded from studies. But, it?s just those differences that may really need to be researched, to make sure girls are being diagnosed and treated correctly.

?Other neuropsychiatric disorders have already made the discovery that symptoms can be different in girls and may require different treatments for girls,? said Dawson, who is also a research professor in the department of psychiatry at the University of North Carolina, Chapel Hill. One such example is attention-deficit/hyperactivity disorder. Girls tend to be less hyperactive than boys, and may instead appear as if they?re daydreaming.

In the latest autism research, the first study compared visual scanning patterns in boys and girls with autism spectrum disorders. Scanning patterns were also collected for typically developing children.

?We used eye-tracking technology while the participants in these studies watched videotapes of social scenes that presented naturalistic stimuli,? said study co-author Ami Klin, director of the Marcus Autism Center, in Atlanta.

The study, which was led by Klin?s student, Jennifer Moriuchi, included 116 school-aged children with autism spectrum disorders. Eighty-one were boys and 35 were girls. The children with autism had varying degrees of social disability. The study also included 36 typically developing children.

?On a surface level, it appears that boys and girls with autism appear to spend equal time learning from the eyes. They did look less than other children,? Klin said. But, when the researchers correlated the youngsters? eye tracking with their level of disability, a much different picture emerged.

?In boys, the more they looked at the eyes, the less socially disabled they are. In girls, the more they looked at the eyes, the more disabled they are,? said Klin, chief of the division of autism and related disorders at Emory University School of Medicine and Children?s Healthcare of Atlanta.

?What the study is suggesting is that we should not automatically assume that boys and girls learn about the world in the same way,? Klin said, adding, ?we have to take gender as a mediating factor.?

Dawson said ?the study found that there are differences in the way girls and boys look at the eyes, so there may be differences in the way autism is manifested in girls than in boys.? She noted that an important criterion right now for diagnosing autism is a lack of eye contact and using the eyes for social cues.

The second study looked at the genetics involved in autism, and potential differences in boys and girls. Yale University researchers analyzed samples from 2,326 families. Included in those samples were those of 2,017 boys and 309 girls with an autism spectrum disorder.

The Yale team found differences between the boys? and girls? genetic samples.

?The fact that autism does affect boys so much more frequently has been staring us in the face for decades. There?s been a hypothesis that there?s something in the extra X chromosome that girls have that may be protective,? Dawson explained. ?The idea is that if you have this protective mechanism in place you may need more risk factors to overwhelm that protective effect and cause autism, and that?s exactly what they found.?

?To develop autism in a girl requires more genetic mutations,? Dawson said. The type of mutations they found are called ?de novo? mutations, she added. This means that the genetic change occurs in the sperm or the egg. It isn?t a gene that?s passed down from the parents. These mutations can occur randomly, or they can be caused by an environmental trigger.

Because these studies are being presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.

More information

Learn more about autism from the U.S. National Institute of Neurological Disorders and Stroke.

HEALTHDAY Web XSmall Girls With Autism May Need Different Treatments Than Boys

Source: http://news.health.com/2013/05/01/girls-with-autism-may-need-different-treatments-than-boys/

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Greater Philadelphia Bicycle News: Rodeo Recap: Girl Scouts Ride ...

We asked our intern Natalie Lang to write about her experience volunteering at the bike rodeo we did with Girl Scouts at Penn last weekend, as part of our Women Bike PHL campaign.

Every semester the Girl Scouts At Penn club partners with local Girl Scout troops for a day-long event where troops can earn patches related to a particular topic. This past weekend the Girl Scouts at Penn partnered with the Bicycle Coalition to present a health and wellness event called Stand Up and Get Fit! The event focused on healthy living and the importance of exercise and sports.

As one portion of the event, The Bicycle Coalition hosted a bike rodeo to teach girls safety both on and off of a bicycle. After a brief introduction, girls were split up into groups that rotated to various stations. The off-bike stations focused on educating the girls about the parts of a bicycle, properly locking a bike and conducting a helmet check. The on-bike stations involved maneuvering, stopping, scanning and signaling.


While I?ve been volunteering at the Bicycle Coalition since March, this was my first time helping outside of the office. When Megan told me about the Stand Up! event I was excited to take a break from the Excel and Word documents in the office and really see what the organization does in the community. When I arrived on Penn?s campus I had no idea what a bike rodeo was or what might be involved. I?ve attended one rodeo my whole life and it involved horses and clowns; I had a feeling neither would be present on Penn?s campus.
While animals and clowns were not present at this rodeo I had just as much fun without them. The Girl Scouts were an amazing group of girls that made the event fly by. While the girls got to eat Lil? Pop Shop popsicles and do yoga at the other stations, most of the girls said their favorite activity was riding bikes. The smiles on the girls' faces proved that overall the event was a huge success! It was a beautiful day and a rewarding experience seeing the girls active and having fun; working at the event only made me wish I had become a Girl Scout when I was younger. If only someone told me there would be bike riding and free popsicles.

Source: http://blog.bicyclecoalition.org/2013/04/rodeo-recap-girl-scouts-ride-with-women.html

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HP may be working on a quad-core 10-inch Android tablet

BERLIN, April 29 (Reuters) - Barcelona will try every trick in the book to overturn a 4-0 first-leg deficit against Bayern Munich in their Champions League semi-final return leg on Wednesday, honorary Bayern president Franz Beckenbauer warned on Monday. Bayern crushed the Spaniards last week in a surprisingly one-sided encounter but Beckenbauer, former player, coach and president of Germany's most successful club, warned that Barcelona were not ready to surrender. "Barca will try everything to throw Bayern off balance," he told Bild newspaper. ...

Source: http://news.yahoo.com/hp-may-working-quad-core-10-inch-android-213016340.html

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Thorsten Heins: tablets aren't a good business model, BlackBerry ...

Thorsten Heins tablets aren't a good business model, BlackBerry aiming to lead mobile computing in five years

Holding out for a post-RIM version of the PlayBook? That waiting likely won't end any time soon. BlackBerry CEO Thorsten Heins used an interview yesterday to discuss the mobile environment five years out. Seems he's feeling particularly bullish about his own company's prospects. "In five years, I see BlackBerry to be the absolute leader in mobile computing -- that's what we're aiming for," he told the interviewer. "I want to gain as much market share as I can, but not by being a copycat."

Not being a copycat may likely involve staying away from the crowded tablet market. "In five years I don't think there'll be a reason to have a tablet anymore," according to the CEO. "Maybe a big screen in your workspace, but not a tablet as such. Tablets themselves are not a good business model." This certainly isn't the first time the exec has expressed caution about the space in the wake of the PlayBook's lukewarm reception. Heins has mentioned in the past that the company won't jump back into tablets unless it sees the potential for profits.

Update: BlackBerry has since issued an official response to the interview,

The comments that Thorsten made yesterday are in line with previous comments he has made about the future of mobile computing overall, and the possibilities that come with a platform like BlackBerry 10. We continue to evaluate our tablet strategy, but we are not making any shifts in that strategy in the short term. When we do have information about our PlayBook strategy, we will share it.

Source: http://www.engadget.com/2013/04/30/blackberry-tablet/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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